• Back Issues >
  • BioOptics World >
  • Volume 7, Issue 3

    • Volume 7, Issue 3

    More content from Volume 7, Issue 3

    Recent developments in optical coherence tomography (OCT) address skin cancer diagnosis.
    May 19, 2014
    1405bownews Fig4
    The Optical Society (OSA; Washington, DC) has honored Rebecca Richards-Kortum, Ph.D., with the 2014 Michael S. Feld Biophotonics Award, recognizing her work in "advancing the ...
    May 19, 2014
    New approvals of biophotonics-based tools by the U.S. Food and Drug Administration include Pinnacle Biologics' premarket supplemental approval for its Optiguide DCYL700 Fiber ...
    May 19, 2014
    Prof. Dr. med. Claus Eckardt used a surgical microscope with integrated heads-up 3D display to perform ophthalmic surgery, which was broadcast live to an audience of 1200 surgeons at Germany's 2014 Frankfurt Retina Meeting. The visualization platform consisted of a Leica Microsystems M822 ophthalmic microscope with integrated TrueVision 3D display technology.
    A surgical microscope with integrated heads-up 3D display was used for the first time to facilitate ophthalmic surgery at the Klinikum Frankfurt Höchst; performed by Prof. Dr....
    May 19, 2014
    "Our vision is to change the course of Alzheimer's disease by enabling early diagnosis at the point of care," Paul Hartung, president and CEO of Cognoptix (Acton, MA) told analysts...
    May 19, 2014
    1405bownews Fig2
    Aerospace, defense, information, and services company Exelis (NYSE:XLS) and private medical imaging company NIRF Imaging have entered into a long-term, exclusive agreement to ...
    May 19, 2014
    Thanks to low quenching, CUBIC is compatible with many fluorescent probes, allowing for longer wavelengths and reducing concern for scattering when imaging the whole brain while inviting multicolor imaging. This image of a marmoset brain was created using the CUBIC method.
    Imaging of whole brains at single-cell resolution normally involves not only preparing a highly transparent sample (to minimize light scattering), but also imaging fluorescence...
    May 19, 2014
    While doing research for security-related radiation detection, University of Texas at Arlington physics professor Wei Chen discovered unexplained decreases in the luminescence...
    May 19, 2014
    1405bowbreak Fig2
    New work in optogenetics "creates a powerful tool that allows neuroscientists to apply a brake in any specific circuit with millisecond precision, beyond the power of any existing...
    May 19, 2014
    1405bowbreakf5
    A device able to detect the earliest signs yet of diabetic retinopathy leverages adaptive optics and promises important implications for the millions of Americans dealing with...
    May 19, 2014
    A new optical method for continuous bedside monitoring of cerebral blood flow (CBF) incorporates a noninvasive probe placed on the surface of a patient's head to measure fluctuations...
    May 19, 2014
    1405bowbreak Fig4
    With standard drug-delivery methods, toxic chemotherapy cocktails affect healthy tissue in addition to cancer.
    May 19, 2014
    Functional connectivity maps in a mouse brain acquired noninvasively by fcPAT depict correlation of the eight main functional regions (a), the four subregions of the somatosensory cortex (b), and the three subregions of the visual cortex (c). The white circles indicate seed regions: S1HL, primary somatosensory cortex – hindlimb region; S1FL, primary somatosensory – forelimb region; S1H, primary somatosensory – head region; S1BF, primary somatosensory – barrel field; V1, primary visual cortex; V2M, secondary visual cortex – medial region; and V2L, secondary visual cortex – lateral region.
    Using optical excitation and acoustic detection, Washington University researchers have developed a functional connectivity photoacoustic tomography (fcPAT) system, which, for...
    May 19, 2014
    1405bowbreak Fig3
    A new method that uses light to control muscles holds potential to restore function to muscle tissue paralyzed by conditions such as spinal cord injury and motor neuron diseases...
    May 19, 2014
    Barbaragoode2
    To offer system and device developers important inspiration and guidance that will help bring to market biophotonics-based tools able to substantially improve the future of healthcare...
    May 19, 2014
    In conjunction with Tumor Paint, a beta version of the Open Air Fluorescence Imager by PerkinElmer facilitates canine cancer surgery at Washington State University Veterinary Teaching Hospital. Animals are injected intravenously with the probe 24 hours prior to surgery. The imager exposes the surgical field of view with an excitation light source matching the spectrum of the probe; fluorescence emission from the probe is captured, spectrally unmixed, and visualized in real time on an LCD monitor.
    A targeted fluorescent probe that seeks and binds tumors achieves several hundred-fold signal amplification to facilitate intraoperative visual discrimination of diseased tissue...
    May 1, 2014
    FIGURE 1. Each panel shows the same object imaged with an increasing exposure, but scaled for identical display; above each image is the minimum and maximum on the full intensity scale. The mean intensity in ADUs (and photons) is shown in the top left of each image. The first image only uses a fraction of the camera's dynamic range, but is still visually acceptable. Although the images look similar, image-scaling can deceive, possibly resulting in the use of an image with fewer photons and therefore lower signal to noise.
    Just like any other tool, having a bit of insight into how scientific imaging cameras work in the context of the project at hand -- from the simplest brightfield application to...
    Feb. 10, 2014