• Bioimaging

    Recent

    Ph.D. student Zane Peterkovic with a photon-counting camera; the screen behind displays the improvement in quality possible with camera optimization.
    With advancing camera technology, wide-field photodetectors with photon-level sensitivity can provide super-resolution, single-molecule tracking, computational imaging, and quantum...
    April 21, 2025
    Credit: Modulight
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    The ML6600 laser module provides 355, 405, 488, 532, 561, and 638 nm, delivered via fiber-coupled or free-space beam options.
    April 11, 2025
    (Image credit: Linkam Scientific)
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    The CMS196V4 stage supports cryo-correlative light and electron microscopy (cryo-CLEM).
    March 31, 2025
    (Image credit: Tomocube)
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    The HT-X1 Plus bioimaging platform is designed for high-resolution, high-throughput 3D imaging of cells and organoids.
    March 21, 2025
    Image provided by Avantier
    Photoacoustic Microscopy
    Photoacoustic Microscopy Photoacoustic microscopy (PAM) is a cutting-edge in vivo tissue imaging technique that combines optical and acoustic methods to break through the optical...
    Feb. 24, 2025
    (Photo credit: Chromacity)
    FIGURE 1. A Chromacity engineer aligns an ultrafast fiber laser with second-harmonic generation.
    Fiber-based ultrafast lasers—with pulses of one-tenth of one-trillionth of a second—continue to evolve, and near-term advances will expand their use to materials processing, nonlinear...
    Feb. 10, 2025

    Highlights

    (Image credit: HÜBNER Photonics)
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    An orange wavelength has been added on the Cobolt 06-01 Series of modulated lasers.
    Dec. 23, 2024
    (Image credit: CRAIC Technologies)
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    The Apollo M confocal Raman microscope is designed for materials research, nanotechnology, and semiconductor analysis.
    Dec. 21, 2024
    (Image credit: Wei Wei and Mei Xueting)
    Depiction of the adaptive sampling scheme, in which a laser beam patterned by a digital micromirror device selectively illuminates neurons and their activity in brain tissue.
    A novel fluorescence microscope offers enhanced insight into how different neurons in the brain communicate and interact.
    Dec. 13, 2024
    (Image credit: Exalos)
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    488-nm Fabry-Perot laser diodes are based on aluminum indium nitride layers.
    Dec. 9, 2024
    (Image credit: Oxford Instruments Andor)
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    The Marana 4.2B-6 back-illuminated 4.2-Mpixel scientific CMOS (sCMOS) model now offers a low noise mode with read noise of 1.0 e-.
    Nov. 21, 2024

    Recommended

    (Image credit: Leica Microsystems)
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    The Mateo FL artificial intelligence (AI)-powered digital fluorescence microscope performs cell culture checks in advanced research applications.
    Oct. 30, 2024
    For 50 years, computed tomography (CT) has been one of the most valuable diagnostic tools and, thanks to photon-counting detectors, the next revolution of computed tomography ...
    Oct. 23, 2024
    The EAGLE C-OCT-S is an athermal, compact spectrometer, suited for spectral-domain optical coherence tomography (OCT).
    Sept. 26, 2024
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    Provided by Avantier
    Avantier Stress-Free Objective Lenses
    In the continuous evolution of optical technology, stress-free objective lenses have emerged as a leading solution, particularly for advanced polarized light microscopy. These...
    Oct. 28, 2024
    © Endeavor Business Media
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    Episode 18 of Following the Photons: A Photonics Podcast features Caroline Boudoux, Ph.D., a renowned leader in the photonics and optics industry.
    Sept. 24, 2024
    (Sample courtesy of Aoi Gohma and Atsushi Miyawaki, RIKEN CBS-EVIDENT Open Collaboration Center)
    FIGURE 1. A 3D image of a live mouse brain acquired using an Evident FV4000 MPE microscope and a 25x TruResolution objective.
    Near-infrared (NIR) imaging can help mitigate the challenges of using visible light as an excitation source for biological research.
    Sept. 11, 2024
    (Image credit: Horiba Scientific)
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    InverTau is a fully software-controlled platform that mounts to the side port of an inverted fluorescence microscope to add fluorescence lifetime imaging (FLIM) capability.
    Sept. 8, 2024
    (Image credit: Prospective Instruments)
    FIGURE 1. 3D volume scan of a xenograft (yellow arrow) model in a zebrafish larvae imaged with TPEF and label-free CARS microscopy; the label-free CARS signal is depicted in red and indicated by pink arrow. Scale bar: 100 µm.
    Advances in microscope technology can improve the efficiency, accuracy, and speed of the biological specimen imaging process.
    Aug. 20, 2024
    (Image credit: AIST)
    FIGURE 1. An international team of researchers has developed a nondestructive and non-labeling rigid endoscope system capable of near-IR hyperspectral imaging from the visible range to over-thousand-nanometer wavelengths.
    Getting deep into the body for the clearest view possible during medical procedures can be key to successful outcomes. This may soon be aided by a new versatile system capable...
    Aug. 16, 2024
    (Image credit: Optotune)
    FIGURE 1. Example of an Optotune liquid lens—the EL-16-40-TC model with thermal compensation.
    How can liquid lenses help with early detection of this potentially life-threatening condition to save lives?
    Aug. 8, 2024
    (Image credit: HÜBNER Photonics)
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    The VALO Tidal ultrafast fiber laser delivers pulse durations of 40 fs (typical) with 2 W output power.
    Aug. 1, 2024