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  • Volume 5, Issue 1
  • Volume 5, Issue 1

    Blue, green, and red spectra correspond to the first, second, and third Raman components, respectively, in spectroscopic signatures of (a) semen, (b) blood, (c) saliva, (d) sweat, and (e) vaginal fluid. Black lines are statistically obtained fluorescent components of sweat and vaginal fluid.
    The ability to analyze body fluid traces is critical for determining the key details of a crime. Now, a combination of advanced statistical methods and multidimensional Raman ...
    Jan. 1, 2012
    (Image courtesy of UVP)
    FIGURE 1: Cellular trafficking of cancer cells within the vasculature of a mouse, which was imaged using UVP’s iBox Explorer in-vivo imager. The imager uses off-the shelf achromatic lenses and other single lenses and filters to form multi-element objectives and tube lenses that can be mixed and matched to provide seven different magnifications. Filter combinations were optimized to ensure good signal-to-noise ratio for each color channel. The GFP-tagged nucleus of the Human HT-1080 fibrosarcoma cell can be seen migrating downstream from the injection site, passing the bifurcation of a distal vein (small green dot, down and to the right of center).
    Some optics manufacturers cite the life sciences market as being a significant driver of their business.
    Jan. 1, 2012
    Molecular imaging has become an important clinical and research tool for the study of heart disease, allowing in-vivo visualization of inflammation and other biological processes...
    Jan. 1, 2012
    (Image courtesy of Adam Wax)
    A new spectroscopic optical coherence tomography (OCT) technique enables imaging of cellular reactions beneath the skin’s surface in true color.
    A new technique—a modified approach to optical coherence tomography (OCT) able to provide cross-sectional images of biomolecules—promises significant implications for both clinical...
    Jan. 1, 2012
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    “The last mile” is term the telecommunications industry uses to describe the critical gap at the end of the line that must be filled for a customer to access enhanced services...
    Jan. 1, 2012

    More content from Volume 5, Issue 1

    (Image courtesy of Biomedical Optics Express)
    A confocal/multiphoton overlay of excised human skin shows skin autofluorescence excited by 405 nm (yellow) and ZnO nanoparticle distribution in skin (stratum corneum) excited by 770 nm (purple), with collagen-induced faint SHG signals in the dermal layer.
    An international research team has leveraged nonlinear optical microscopy to study the effect of zinc oxide (ZnO) nanoparticles in sunscreen that have raised a debate over product...
    Jan. 1, 2012
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    You’ve heard of a lab on a chip: Now a group of researchers have developed a “lab on a bubble” approach to quickly concentrate samples in order to detect biological molecules....
    Jan. 1, 2012
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    Recognizing that traumatic brain injuries need instant diagnosis followed by the proper treatment in a clinical setting, a research team has developed a near-infrared (NIR) device...
    Jan. 1, 2012
    1201bowprod Lumencor
    An alternative to arc lamps, the SOLA solid-state light engine produces continuous white light from 380 to 680 nm for imaging common fluorophores and fluorescent proteins.
    Jan. 1, 2012
    Using optogenetics, a Swiss research team has at last proven the long-suspected link between cocaine use and physical brain change.
    Jan. 1, 2012
    The full-day 15th annual Future of Light Symposium, held December 1, 2011, at Boston University’s Photonics Center, explored topics in neurophotonics, providing a specific focus...
    Jan. 1, 2012
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    A new, label-free imaging tool that tracks single-walled carbon nanotubes (SWNT) in both living cells and the bloodstream could help to boost the use of the nanotechnology in ...
    Jan. 1, 2012
    Robert Alfano
    During BiOS 2011, SPIE announced the launch of the Britton Chance Biomedical Optics award, to honor the memory of the prolific researcher, instructor, and leader whose contributions...
    Jan. 1, 2012
    Quantum dots are so tantalizing: The nanoscale semiconductor crystals glow more intensely, and for longer time periods, than do fluorescent probes.
    Jan. 1, 2012
    For the University of Southampton’s Optoelectronics Research Centre, the new year launches a five-year, £2.6 million ERC Advanced Grant designed to advance biophotonics research...
    Jan. 1, 2012
    (Image courtesy of J. Kevin Fitzsimons, Ohio State University)
    FIGURE 1. Allen Yi and Lei Li inspect a prototype lens that can be used to create three-dimensional images.
    Innovative researchers are bringing depth into focus for three-dimensional imaging. Using a variety of tools including novel optics, light patterning, and software, they combine...
    Jan. 1, 2012
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    In-vivo bioimaging is one of the applications promised by a new near-infrared (NIR) phosphor that glows for up to two weeks after a one-minute exposure to sunlight or even indoor...
    Jan. 1, 2012
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    A new era has dawned in optical coherence tomography (OCT). Fourier domain mode-locking (FDML) lasers enable sustained imaging rates about 50x that of any other source, with comparable...
    Jan. 1, 2012
    Leica Microsystems will provide next-generation g-STED (gated stimulated emission depletion), licensed from the Max Planck Society and the German Cancer Research Center, in a commercial system that promises to improve resolution and contrast for continuous-wave STED while reducing laser intensity.
    As ever, it was difficult to find technology in the conference program at the Society for Neuroscience’s 2011 annual meeting (November 12–16, 2011). The presentations focused ...
    Jan. 1, 2012
    FEI’s new MAPS (Modular Automated Processing System) correlative workflow system helps researchers see both large-scale context and small-scale detail in one view.
    A session on quantitative live cell microscopy by researchers from Harvard Medical School—presented during the American Society for Cell Biology (ASCB) annual meeting (December...
    Jan. 1, 2012