Three winners have been named in the 2016 SPIE Startup Challenge during SPIE Photonics West. Double Helix of Colorado won the grand prize with its 3D biophotonics system that can image at the single-molecule level inside individual cells. Mayland-based Diagnostic anSERS placed second with its marijuana breathalyzer. And third was Disease Diagnostic Group, with its diagnostic tool made from refrigerator magnets and a laser pointer.