The pE-10 is a 10-channel LED Illumination System developed for manufacturers of multiplex imaging platforms. Covering wavelengths from UV right up to 850 nm, the pE-10 enables high-plex fluorescence imaging at the hardware level, allowing OEMs to deliver robust, reproducible data for spatial biology applications, without reliance on complex post-processing.  

Fluorescence imaging systems for spatial biology demand higher plex counts with speed, reproducibility and quantitative confidence. While advances in image analysis often take centre stage, the optical foundation – specifically the illumination system and optical filters – are key in defining system performance and data validity across instruments, laboratories and timepoints.

The arrival of the pE-10 brings simultaneous control of ten individual LEDs, boosting throughput by capturing multiple targets in a single acquisition. When paired with the Kromnigon SpectraSplit^® 10 optical filters, each LED is carefully tuned for superior spectral separation to deliver clean, high-quality images directly at acquisition. Resolving signals in hardware provides confidence that data accurately represents the underlying biology, which is essential across spatial biology applications, from discovery through to translational studies and regulated clinical pathology.

The pE-10 is available alongside Kromnigon SpectraSplit10 filters, and supports a range of validated fluorophores, making it simple to implement across diverse laboratory environments.