• Fluidigm Corporation

    7000 Shoreline Court Suite 100
    South San Francisco, CA 94080
    United States
    650-266-6000
    650-871-7152
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    Articles

    Tumisu/Pixabay
    Job 4131482 1920
    The collaboration will focus on cytometry by time-of-flight (CyTOF)-based research performed in the Karolinska Institutet’s Department of Women’s and Children’s Health.
    Covid 19 5152317 1920
    Imaging mass cytometry enabled the researchers to view not only the structure of the tissue, but also the interplay between infected cells and the immune system in COVID-19 patients...
    Covid 19 4982910 1920
    Mass cytometry technology from Fluidigm is being used in a prospective observational cohort surveillance study of up to 2000 adult participants hospitalized with COVID-19.
    FIGURE 1. Imaging Mass Cytometry (IMC) begins with the user loading a slide prepared with an antibody-stained specimen into the Hyperion Imaging System and using system controls to select a region of interest to be imaged (a). The system’s pulsed laser, operating at 213 nm, enables precise imaging: The beam, focused at 1 µm diameter, samples proteins stained with metal-tagged antibodies and directs these tags to analysis by inductively coupled time-of-flight (ToF) technology. This occurs in a single scan as the laser samples each squared-micron pixel in the selected region (b).
    The integration of novel laser ablation and mass cytometry enables spatial resolution of single-cell phenotypes, promising a new advance for cancer diagnostics and therapy.

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