Articles

Bio&Life Sciences

Fluidigm, Karolinska Institutet collaboration to accelerate cytometry technology

The collaboration will focus on cytometry by time-of-flight (CyTOF)-based research performed in the Karolinska Institutet’s Department of Women’s and Children’s Health.

Biophotonics Techniques

Imaging cytometry details lung tissue changes at single-cell level in COVID-19 patients

Imaging mass cytometry enabled the researchers to view not only the structure of the tissue, but also the interplay between infected cells and the immune system in COVID-19 patients...

Biophotonics Techniques

Multisite COVID-19 patient study uses mass cytometry technology

Mass cytometry technology from Fluidigm is being used in a prospective observational cohort surveillance study of up to 2000 adult participants hospitalized with COVID-19.

FIGURE 1. Imaging Mass Cytometry (IMC) begins with the user loading a slide prepared with an antibody-stained specimen into the Hyperion Imaging System and using system controls to select a region of interest to be imaged (a). The system’s pulsed laser, operating at 213 nm, enables precise imaging: The beam, focused at 1 µm diameter, samples proteins stained with metal-tagged antibodies and directs these tags to analysis by inductively coupled time-of-flight (ToF) technology. This occurs in a single scan as the laser samples each squared-micron pixel in the selected region (b).

Test & Measurement

Tumor architecture insights advance cancer diagnosis and treatment

The integration of novel laser ablation and mass cytometry enables spatial resolution of single-cell phenotypes, promising a new advance for cancer diagnostics and therapy.

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