Ophthalmic optogenetics company raises $6M in funding

Nov. 19, 2015
RetroSense Therapeutics has secured $6 million to further investigate the use of gene therapy and optogenetics to restore vision.

Biopharmaceutical company RetroSense Therapeutics (Ann Arbor, MI) has secured $6 million in Series B financing to further investigate the use of gene therapy and optogenetics to restore vision.

Related: Optogenetics tools address a growing range of applications

Earlier in 2015, the company closed $7 million in Series A financing, bringing the total Series A and Series B investment to $13 million. Total net proceeds should enable completion of the company’s recently initiated Phase I/II clinical study for its lead compound, RST-001, for treatment of retinitis pigmentosa, a genetic condition that leads to the progressive degeneration of rod and cone photoreceptors and eventually results in severe vision loss and blindness. The funding will also support the further development of a second promising gene therapy candidate.

The FDA granted Orphan Drug Designation to RST-001 in 2014 and authorized first-in-human clinical trials for the product in 2015. Recruitment for the Phase I/II clinical study (NCT02556736) is currently underway. RST-001 is expected to have application to all forms of retinitis pigmentosa, independent of an individual’s causative gene or mutation. RST-001 is being developed as a first-in-class gene therapy application of optogenetics designed to restore vision to those affected by retinal degenerative conditions.

For more information, please visit www.retro-sense.com.

About the Author

BioOptics World Editors

We edited the content of this article, which was contributed by outside sources, to fit our style and substance requirements. (Editor’s Note: BioOptics World has folded as a brand and is now part of Laser Focus World, effective in 2022.)

Sponsored Recommendations

Melles Griot® XPLAN™ CCG Lens Series

March 19, 2024
IDEX Health & Science sets a new standard with our Melles Griot® XPLAN™ CCG Lens Series fluorescence microscope imaging systems. Access superior-quality optics with off-the-shelf...

Spatial Biology

March 19, 2024
Spatial Biology refers to the field that integrates spatial information into biological research, allowing for the study of biological systems in their native spatial context....

Fluorescent Protein Optical Imaging Considerations

March 19, 2024
What factors should you consider when your incorporate fluorescent proteins in an optical imaging application? Learn more.

Custom-Engineered Optical Solutions for Your Application

March 19, 2024
We combine advanced optical design and manufacturing technology, with decades of experience in critical applications, to take you from first designs to ongoing marketplace success...

Voice your opinion!

To join the conversation, and become an exclusive member of Laser Focus World, create an account today!