Coherent laser for cytometry applications

The Genesis CX355 -250 laser from Coherent Inc. (Santa Clara, CA) (Nasdaq: COHR) delivers more than 250 mW of TEM₀₀ output. In the Genesis CX355 -250, the inherent advantages of optically pumped semiconductor laser (OPSL) technology provide the ideal combination of low noise (<0.5%) and high output power, which enables OEM instruments to achieve superior signal to noise characteristics. Moreover the Genesis CX355 -250 produces a TEM₀₀ output beam (M² < 1.2) enabling perfect collimation and/or refocusing to a diffraction-limited spot.

The major applications that will benefit from the high power of the Genesis CX355 -250 are in flow cytometry of live-cells, such as egg and fertilized-egg sorting, where the peak power of older, mode-locked lasers poses significant risk of mutagenic damage to the DNA in the sorted cells. Other applications include use in high-throughput cytometers incorporating two parallel laser interaction cells and as a source for other fluorescence-based applications, including confocal microscopy.