Fluorescence microscopy method pinpoints the positions of individual molecules in living cells

July 18, 2016
Anyone who has ever taken a group photo will be familiar with the problem: If everyone is constantly running around, it's almost impossible to get a sharp photo. Cell biologists who want to visualize molecular processes inside cells face a similar challenge.
Anyone who has ever taken a group photo will be familiar with the problem: If everyone is constantly running around, it's almost impossible to get a sharp photo. Cell biologists who want to visualize molecular processes inside cells face a similar challenge.
The BioOptics World take on this story:

Dynamic molecular patterns in cells are difficult to observe by fluorescence microscopy alone, as molecules are too numerous and their movements are too fast. Recognizing this, researchers at the Max Planck Institute developed a method that allows them to observe nanometer-sized patterns of biomolecules such as proteins in an arrested but living state. By lowering the temperature of living cells to completely suspend the macromolecular motion in cells, it yields a sufficient amount of time to capture high-resolution images of molecular patterns. With the method, the researchers could obtain multiple snapshots to reveal motion patterns.

Sponsored Recommendations

Request a quote: Micro 3D Printed Part or microArch micro-precision 3D printers

April 11, 2024
See the results for yourself! We'll print a benchmark part so that you can assess our quality. Just send us your file and we'll get to work.

Request a free Micro 3D Printed sample part

April 11, 2024
The best way to understand the part quality we can achieve is by seeing it first-hand. Request a free 3D printed high-precision sample part.

How to Tune Servo Systems: The Basics

April 10, 2024
Learn how to tune a servo system using frequency-based tools to meet system specifications by watching our webinar!

Precision Motion Control for Sample Manipulation in Ultra-High Resolution Tomography

April 10, 2024
Learn the critical items that designers and engineers must consider when attempting to achieve reliable ultra-high resolution tomography results here!

Voice your opinion!

To join the conversation, and become an exclusive member of Laser Focus World, create an account today!