Claude Boccara

Honorary Dean of Research

Full-field optical coherence tomography (FF-OCT) is an en face, broadband interferometric imaging approach that offers many advantages for life-science applications, including fast tissue imaging at the cellular level. Like other OCT approaches, it provides the benefits of noninvasive, nondesctructive in-vivo imaging, but unlike the others, FF-OCT images in the transverse orientation and thus enables high lateral resolution.

This webcast will discuss the “whys” and the “hows” of FF-OCT including basic principles of the setup and elementary signal processing. It will also report recent advances and applications--including endoscopic adaptation, tissue elasticity mapping, and multimodal imaging--along with more established applications in clinical research (breast, brain and kidney), dermatology/cosmetology (both in-vivo and ex-vivo), and animal models for developmental biology.

FIGURE 1. What looks like a more traditional OCT image (left) is actually a reconstruction of all slices registered during Cell OCT imaging of a rat’s anterior eye (cornea). The Cell OCT approach enables cellular-resolution views of transverse slices (right).
Test & Measurement

OPTICAL COHERENCE TOMOGRAPHY: Full-field OCT approaches clinical application

April 1, 2009
Newly developed Cell OCT, an approach to full-field optical coherence tomography, has enabled researchers to image breast-cancer tissue with histology-like results.