AUGUST 27, 2009--Biomedical researchers at the University of Arkansas and University of Arkansas for Medical Sciences in Little Rock have developed a special contrast-imaging agent that is capable of molecular mapping of lymphatic endothelial cells and detecting cancer metastasis in sentinel lymph nodes. The new material could be used as a more efficient and less toxic alternative to nanoparticles and fluorescent labels used in the non-invasive, targeted molecular detection of normal cells, such as immune-related cells, and abnormal cells, such as cancer cells and bacteria. Findings were published Sunday in Nature Nanotechnology.