We look forward to safely gathering 17—22 July 2022 in Montréal, Québec, Canada, for SPIE Astronomical Telescopes + Instrumentation, the most valuable technical event for ground-based, airborne, and space-based telescopes, and their supporting instrumentation. The 2022 call for papers is open, and we encourage researchers and engineers to share advancements, discoveries, challenges, and project updates with the community.