Highlights

(Courtesy of J. Chen et al., Nat. Methods; doi:10.1038/s41592-023-01820-3)
FIGURE 1. An optomechanical design of the SMURF two-photon microscope.
Bio&Life Sciences

A brain imaging trifecta

July 13, 2023
An approach to imaging electrical activity deep in the brain makes neurological studies more effective and less invasive.
(Photo credit: Henry Lam/Fleming Group)
Scientists Graham Fleming (left) and Quanwei Li in the lab with their quantum light spectroscopy setup.
Test & Measurement

A single photon initiates photosynthesis

June 30, 2023
Quantum light spectroscopy, a new tool under development, reveals quantum dynamics at play during photosynthesis.
(Courtesy of Arkansas State University/Arkansas Research Alliance)
Arkansas State University uses lasers to measure the physical characteristics of cells with a flow cytometer.
Bio&Life Sciences

Advancements in laser tech impacting flow cytometry

June 19, 2023
Flow cytometry enables rapid and precise analysis of complex samples. At the core of flow cytometry performance lies the light source used for fluorophore excitation, with lasers...
(Courtesy of Anna Maria Reuss, Fabian Voigt)
Detailed image of neurons in a mouse brain, as captured using the Schmidt objectives.
Bio&Life Sciences

Schmidt telescope, scallop eyes transform microscope objectives

May 22, 2023
Drawing inspiration from the uniqueness of scallop eyes, neuroscientists in Switzerland have developed microscope objectives that could make imaging samples simpler, cheaper, ...
(Courtesy of Ian Shih, UNC School of Medicine)
FIGURE 1. The experimental fMRI-fiber photometry platform could offer a deeper understanding of the dynamic properties of brain states and their relationship to behaviors.
Bio&Life Sciences

Spectrally resolved fiber photometry system enables exploring the brain’s networks

April 24, 2023
An optical fiber-based platform may lead to brain network-based treatment regimens for neuropsychiatric and neurological disorders.
Leica Microsystems
Bio&Life Sciences

Digital microscope designed for cell culture routine use

March 18, 2023
The Mateo TL digital transmitted light inverted microscope is designed for use in cell culture routine.
(Courtesy of Jesús Pineda/University of Gothenburg)
FIGURE 1. A depiction of cells exploring a landscape composed of graph networks.
Bio&Life Sciences

AI and microscopy may revolutionize study of cells, molecule behavior

March 6, 2023
Researchers at the University of Gothenburg in Sweden tap artificial intelligence (AI) to overcome challenges that have long plagued the study of living cells.
(Courtesy of Harsharan Singh Bhatia and Ali Ertürk, Helmholtz Munich)
Aortic regions of a human heart whose vascular plaques have been analyzed by DISCO-MS, a 3D spatial-omics technology that uses robotics to acquire proteomics data from cells identified early in diseases.
Bio&Life Sciences

Spatial-omics explores cellular organization and interactions within tissues

Feb. 15, 2023
Using spatial-omics, researchers could detect and analyze disease biomarkers at early stages of development, ultimately leading to quicker, more effective treatments.
(Courtesy of Johns Hopkins University)
With their new technique, the researchers viewed a zebrafish larvae, capturing whole-body volumetric recordings of its neural activity.
Bio&Life Sciences

Mesoscopic imaging method offers unprecedented cell views

Jan. 19, 2023
A new type of light-sheet microscopy provides a more comprehensive, distinct look than ever before at natural cell interactions.