• Bioscience

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    Credit: Lumencor
    lumencor
    The VOLTA Scanner simultaneously monitors cellular function with submillisecond temporal resolution in 96- and 384-microwell plates.
    May 11, 2025
    Ph.D. student Zane Peterkovic with a photon-counting camera; the screen behind displays the improvement in quality possible with camera optimization.
    With advancing camera technology, wide-field photodetectors with photon-level sensitivity can provide super-resolution, single-molecule tracking, computational imaging, and quantum...
    April 21, 2025
    (Image credit: Inno-Spec)
    innospec
    The BlueEye UV hyperspectral imaging system operates from 220 to 380 nm.
    April 1, 2025
    (Image credit: Linkam Scientific)
    linkam
    The CMS196V4 stage supports cryo-correlative light and electron microscopy (cryo-CLEM).
    March 31, 2025
    (Image credit: Tomocube)
    tomocube
    The HT-X1 Plus bioimaging platform is designed for high-resolution, high-throughput 3D imaging of cells and organoids.
    March 21, 2025
    (Image credit: HÜBNER Photonics)
    hbner_photonics
    An orange wavelength has been added on the Cobolt 06-01 Series of modulated lasers.
    Dec. 23, 2024

    Highlights

    (Image credit: CRAIC Technologies)
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    The Apollo M confocal Raman microscope is designed for materials research, nanotechnology, and semiconductor analysis.
    Dec. 21, 2024
    (Image credit: Wei Wei and Mei Xueting)
    Depiction of the adaptive sampling scheme, in which a laser beam patterned by a digital micromirror device selectively illuminates neurons and their activity in brain tissue.
    A novel fluorescence microscope offers enhanced insight into how different neurons in the brain communicate and interact.
    Dec. 13, 2024
    (Image credit: A. Stevens et al., Bioeng. Transl. Med.; https://doi.org/10.1002/btm2.10727)
    H&E staining on rat brain coronal slices from all treatment conditions at three days post-injury and four weeks post-injury. Images were taken from frontal cortex, corpus callosum, and choroid plexus (body of the lateral ventricle).
    Photobiomodulation could soon expand its effectiveness beyond tissue repair and pain management into the brain.
    Nov. 25, 2024
    (Image credit: Oxford Instruments Andor)
    oxford_instruments_andor
    The Marana 4.2B-6 back-illuminated 4.2-Mpixel scientific CMOS (sCMOS) model now offers a low noise mode with read noise of 1.0 e-.
    Nov. 21, 2024
    (Image credit: Leica Microsystems)
    leica_microsystems
    The Mateo FL artificial intelligence (AI)-powered digital fluorescence microscope performs cell culture checks in advanced research applications.
    Oct. 30, 2024

    Recommended

    (Sample courtesy of Aoi Gohma and Atsushi Miyawaki, RIKEN CBS-EVIDENT Open Collaboration Center)
    FIGURE 1. A 3D image of a live mouse brain acquired using an Evident FV4000 MPE microscope and a 25x TruResolution objective.
    Near-infrared (NIR) imaging can help mitigate the challenges of using visible light as an excitation source for biological research.
    Sept. 11, 2024
    InverTau is a fully software-controlled platform that mounts to the side port of an inverted fluorescence microscope to add fluorescence lifetime imaging (FLIM) capability.
    Sept. 8, 2024
    Conventional detection methods used to identify pathogens in food, such as DNA sequencing and cell cultures, are effective, but contamination can happen. A 3D-printed microfluidic...
    Aug. 9, 2024
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    (Photo credit: Tsinghua University)
    Lingjie Kong (left), associate professor at Tsinghua University’s Precision Instrument Department.
    Researchers in China create a new mesoscopy method to record in vivo biodynamics over a large scale at high spatiotemporal resolutions.
    June 27, 2024
    (Image credit: XIMEA)
    ximea
    The MX081 UV camera models provide a spectral range from 200 to 400 nm.
    June 5, 2024
    (Image credit: IN-VISION Technologies)
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    The HELIOPORA light engine offers resolutions to 300 nm for cybergenetics and optogenetics research.
    June 3, 2024
    lumencor
    Volta’s two-laser optical system contains 462 and 660 nm diode lasers, and offers 96- or 384-well microplate configurations.
    Feb. 7, 2024
    leica_microsystems
    Aivia AI image analysis software version 13 is a complete 2-to-5D image visualization, analysis, and interpretation platform.
    Feb. 1, 2024
    FIGURE 3. 4D image of a dividing cell that was detected by Aivia in a feedback loop with LAS X from Leica Microsystems.
    Microscopy enabled by artificial intelligence (AI) will improve life sciences research and development across key therapeutic categories. Promising developments include autonomous...
    Nov. 7, 2023
    (Courtesy of Gowerlabs)
    FIGURE 1. The researchers use LUMO, a wearable, portable, high-density functional NIR imaging device equipped with modular tiles with built-in NIR light sources and detectors.
    New work by a U.K. team demonstrates a new technique that enables a more detailed view of brain function, which could lead to more accurate and earlier diagnosis of diseases that...
    Sept. 29, 2023
    (Image credit: Lingjie Kong)
    FIGURE 1. Schematic of neurochemical sensing in vivo with FOPECs.
    Researchers in China develop fiber-optic tool based on engineered cells (FOPECs) for real-time sensing of neurochemicals at high specificity in a variety of animal species and...
    July 20, 2023