Super-resolution images from a standard microscope
OCTOBER 23, 2009--Carl Zeiss MicroImaging GmbH (Jena, Germany) has received a license from the University of California for the commercialization of a super-resolution microscopy technique called Structured Illumination Microscopy (SIM).
SIM was developed by scientists Mats G.L. Gustafsson, John W. Sedat, and David A. Agard at the University of San Francisco (UCSF).
The technology overcomes the classical diffraction limit to microscopic resolution by combining a special illumination pattern with computational image analysis. Compared to a conventional microscope, the resulting superresolution images have up to double the resolution in all three spatial directions.
The agreement grants Carl Ziess the right to integrated the SIM technique into its microscope systems.