Revealing Cellular Mysteries With Ultrafast Lasers

A new generation of compact ultrafast laser systems capable of simultaneous two- and three-photon microscopy—including 2 photon fluorescence (2PF), second harmonic generation (SHG), 3 photon fluorescence (3PF) and third harmonic generation (THG) imaging—offer exciting potential to accelerate biomedical research and clinical diagnostics.

In this white paper we introduce the femtosecond laser which is helping enable such higher harmonic generation imaging systems, that can provide in situ tissue analysis during bronchoscopy procedures or other procedures where tissue is excised.