From Microtoroids to Single Molecules: Modeling-Enabled Ultrasensitive Optical Sensing

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Whispering-gallery-mode (WGM) microtoroid resonators confine light in extremely small volumes for extended periods of time, creating strong light–matter interactions and exceptional sensitivity to nanoscale perturbations. The Little Sensor Lab harnesses these properties through the frequency-locked optical whispering evanescent resonator (FLOWER) platform for ultrasensitive biomedical diagnostics, cutting-edge drug discovery, and early-warning toxic gas detection.
In this webinar, Dr. Judith Su, Craig M. Berge Faculty Fellow and Associate Professor of Optical Sciences and Biomedical Engineering at the University of Arizona, where she directs the Little Sensor Lab will discuss development of microtoroid-based optical sensors and how modeling and simulation complement experiments throughout this process. Examples will illustrate how simulations of optical fields and resonator behavior help us understand interactions between light and nanoscale objects, interpret experimentally measured signals, and explore sensor designs and operating conditions. Professor Su will highlight how these computational insights connect with experimental measurements and have helped guide the evolution of the FLOWER platform toward increasingly sensitive measurements.
The talk will focus on the physical insights gained from combining modeling with experiment, rather than on specific simulation techniques. Attendees will see how computational modeling can provide physical intuition, inform experimental design, and help translate the extraordinary sensitivity of microtoroid resonators into practical tools for investigating nanoscale and molecular phenomena.


