Articles and News - Biophotonics

Part of a frequency comb instrument used to measure trace gases for biomedical applications, the beam from a powerful fiber laser is converted by a special crystal and other optics into two light waves at lower frequencies

Laser frequency comb enables high-level disinfection of harmful bacteria


The laser frequency comb is helping researchers at JILA evaluate a novel instrument that kills harmful bacteria without the use of liquid chemicals or high temperatures.

Schematic representation of the experimental setup at the Linac Coherent Light Source, where millions of tiny crystals are injected into the free-electron laser beam in a thin, liquid jet

Free-electron lasers reveal architecture of proteins in unprecedented detail

06/04/2012 Researchers from the Max Planck Institute for Medical Research (MPI) and the Max Planck Advanced Study Group have analyzed protein crystals using short pulses of x-ray light from the world's first hard x-ray free-electron laser...
An assembled flow cytometry chip with size comparable to a U.S. quarter

Tiny flow cytometry chip could yield faster, cheaper diagnosis of leukemia, HIV


A flow cytometry chip that can produce 3D focusing of a stream of cells developed by researchers at Penn State University may make rapid screening of cells for leukemia or HIV possible.

Under green fluorescent light, microtubuli (shown) and other cell structures can be observed in living fish embryos

Microscopy method peers into cell structures of living fish

05/17/2012 Researchers from the Karlsruhe Institute of Technology, the Max Planck Institute for Polymer Research, and the American National Institutes of Health have developed a new microscopy method to visualize cell structures measuring...
Postdoctoral researcher Steven Adie, professor P. Scott Carney, graduate students Adeel Ahmad and Benedikt Graf, and professor Stephen Boppart, all of the University of Illinois, developed a method to computationally correct aberrations in 3D tissue microscopy

Adaptive optics, computer software pair to correct aberrations in optical imaging


University of Illinois researchers have developed a technique to computationally correct for aberrations, enabling higher-quality images and 3D datasets in real-time imaging applications such as image-guided surgery.

An artistic representation of the cutting method used to measure the microtubules' lengths

Femtosecond laser ablation sheds new insight on cell division

04/27/2012 Researchers at the Harvard School of Engineering and Applied Sciences (SEAS), using a femtosecond laser, sliced through and made quantitative measurements of the mitotic spindle (an apparatus that forms during cell division), d...
The 9.6 mm probe housing (right) next to the housing of the earlier prototype 18 mm probe (left) showing the reduction in packaged probe size

Femtosecond probe with 'lightsaber'-like precision promising for laser surgery

04/24/2012 Researchers from the University of Texas at Austin have developed a small, flexible endoscopic medical device fitted with a femtosecond laser "scalpel" that can remove—with 'lightsaber'-like precision—diseased or dama...
Professor Tuan Vo-Dinh discusses results from his NanoSight NS500 with Dr. Hsiangkuo Yuan from his research group

Nanoparticle tracking helps characterize 'nanoconstructs' for biomedical applications

04/19/2012 Scientists at Duke University's Fitzpatrick Institute for Photonics, led by Professor Tuan Vo-Dinh, applied nanoparticle tracking analysis (NTA) to characterize metal nanoparticle construct materials for use in biosensing, imag...
The difference between an infected red blood cell (top) and a healthy cell (bottom) is revealed by secondary speckle sensing microscopy (S3M)

Microscopy technique could detect malaria in a half-hour's time


Researchers at the Materials Technology Institute of the National Research Council have developed a microscopy system that could diagnose malaria much faster and with greater accuracy.

A hyperspectral line camera with four broadband light sources acquires images with the lens at center

Hyperspectral imaging device helps debunk wound healing


Hyperspectral imaging (HSI) devices, calibrated to new National Institute of Standards and Technology (NIST) standard reference spectra, bring forth new insight on the physiology of tissue injury and healing.

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