Articles and News - Biophotonics

Sasi Palaniyappan and Rahul Shah inside a target chamber where the TRIDENT terawatt laser is aimed at a very thin foil target

Terawatt laser sheds light on laser-plasma interaction for cancer therapy development

08/21/2012 Scientists at the Los Alamos National Laboratory (LANL) have observed for the first time how a laser penetrates dense, electron-rich plasma to generate ions. The process has applications for developing next-generation particle ...
The ultraviolet C (UVC) pulse flash irradiation only selectivity caused death of neoplastic cells, and not non-neoplastic cells

Cancer therapy method uses UVC pulse flash irradiation to destroy neoplastic cells

08/21/2012

Scientists at the Tokai University School of Medicine in Japan have developed a new cancer therapy method using ultraviolet C (UVC) pulses of light.

Live cells incubated with the polymer nanoparticles. The green color is the fluorescence coming from the molecules trapped within the nanoparticles

Switchable, glowing molecules promising for fluorescent probes

08/16/2012 Scientists at the University of Miami college of Arts and Sciences have developed a method of switching fluorescent molecules on and off within aqueous environments, strategically trapping the molecules inside water-soluble par...
Iowa State University and Ames Laboratory researchers Sanjeevi Sivasankar, Chi-Fu Yen, and Hui Li have invented a microscopy method—standing wave axial nanometry (SWAN)—to study single biological molecules

Dual microscopy method studies single biological molecules

08/06/2012

Pairing atomic force microscopy (AFM) and optical microscopy, researchers have developed a way to complete 3D measurements of single biological molecules with unprecedented accuracy and precision.

Schematic illustration of a hollow fiber. The chemiluminescent liquid in the core (yellow) is guided through the fiber, also with help of further hole structures (dark blue)

Liquid-filled hollow optical fibers show promise for biosensing

08/01/2012

Xia Yu and colleagues at the A*STAR Singapore Institute of Manufacturing Technology have developed an optical fiber system that can deliver light to microfluidic chips, or biosensors, with high efficiency.

Nano-FTIR chemically identifies nanoscale sample contaminations, as shown in the AFM images of a polymethylmethacrylate (PMMA) film on a silicon surface

Optical microscopy, spectroscopy duo IDs materials at the nanoscale

07/30/2012

An international team of researchers have developed an optical instrument that can chemically identify materials at the nanometer scale.

A novel microscopy approach—fluorescence correlation spectroscopy coupled with calibrated imaging—revealed the number of Cse4 molecules within single centromeric nucleosomes over the course of the cell cycle

Microscopy method determines how centromere structure forms

07/20/2012 Scientists at the Stowers Institute of Medical Research have developed a microscopy method—pairing fluorescence correlation spectroscopy (FCS) with calibrated imaging—to count the number of fluorescent molecules in a cluster, a...
High-performance lasers are promising and compact proton sources that could be used in future cancer therapies

Promising for cancer therapy, terawatt laser enables higher energies for particle acceleration

07/02/2012 Physicists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) directed light from the Dresden Laser Acceleration Source (DRACO) perpendicularly and obliquely onto a thin metal foil, allowing them to demonstrate for the first ti...
Comparison of a SLIM and dSLIT image of an E. coli cell

3D microscopy technique visualizes sub-cellular structure of E. coli noninvasively

06/29/2012

Researchers at the University of Illinois at Urbana-Champaign have created a fast, noninvasive 3D microscopy technique for visualizing, quantifying, and studying cells without the use of fluorescence or contrast agents.

Sony’s prism array, coupled with a 32-channel photomultiplier tube, divides fluorescence emissions of all fluorophores to detect full-spectrum fluorescent emissions in complex cell analysis

Sony to develop 'spectral' cytometry instrument

06/19/2012

Sony is developing a ‘Spectral’ cell analyzer, its second flow cytometry instrument for optical analysis of cells to date.

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